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Ambien (zolpidem) cannot be ordered online through digital care services without a valid EPCS prescription from a DEA-registered US healthcare provider, as it is a Schedule IV controlled substance for short-term insomnia; no-rx "convenient" access violates 21 U.S.C. § 841 federal felony laws with up to 20-year penalties.
Legitimate telemedicine requires ISI ≥10 sleep diary verification, PDMP clearance, and physician video consultation under 2025 rules—no digital flow bypasses Ryan Haight in-person exam post-flex or boxed warnings for sleep-driving/parasomnias.
Zolpidem (selective GABA-A α1 agonist), Tmax 1.6h IR, t½ 2.5h; 15-25% dependence >2 weeks, next-day impairment—discontinue if complex behaviors; contraindicated myasthenia gravis, severe respiratory issues.
Diagnosis: ISI ≥10 + CBT-I failure.
Screening: PDMP clean, negative UDS.
EPCS: #30 tabs ≤14 days pharmacy fill.
Follow-up: q7d efficacy check.
| Incidence | Domain | Accelerators | Protocols |
|---|---|---|---|
| 20-40% | Drowsiness | Women >5mg | 5mg dose cap |
| 10-25% | Sleep-driving | Alcohol | Contraindicated |
| 5-15% | Falls | Elderly | Bedtime only |
Digital care absent EPCS constitutes CSA Schedule IV felony.
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