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Subutex is a prescription medication containing buprenorphine, used primarily in the treatment of opioid use disorder. Buprenorphine is a partial opioid agonist, which means it activates opioid receptors in the brain but produces a ceiling effect that reduces the risk of misuse, overdose, and respiratory depression compared to full opioid agonists. Overview of Subutex Subutex is part of medication-assisted treatment (MAT) for opioid dependence. It helps reduce withdrawal symptoms and cravings, making it easier for patients to transition away from illicit opioid use. Subutex is a critical tool in the treatment of opioid use disorder, helping patients manage withdrawal symptoms and cravings safely. Safe and effective use requires strict adherence to prescribed dosages, medical monitoring, and participation in behavioral therapy or support programs. Patients should never attempt to use Subutex without a prescription or medical supervision, as misuse can result in serious health risks, addiction, or overdose.