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Alprazolam, commonly known by the brand name Xanax, is a prescription medication belonging to the benzodiazepine class of drugs. It is primarily used for the short-term treatment of anxiety disorders and panic disorders. Key Information Mechanism of Action: Alprazolam works by enhancing the effects of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA), which helps to slow down the central nervous system, producing a calming effect. Uses: It is FDA-approved for the management of generalized anxiety disorder (GAD) and panic disorder, including those with agoraphobia. It is sometimes used off-label for conditions such as premenstrual syndrome (PMS) or anxiety associated with depression. Forms: It is available in various forms, including immediate-release (IR) tablets, extended-release (XR) tablets, orally disintegrating tablets, and an oral solution. Important Warnings Alprazolam has several boxed warnings (the FDA’s strictest warning) due to potential risks: Dependence and Withdrawal: Long-term use can lead to physical and psychological dependence. Suddenly stopping the medication can cause severe, potentially life-threatening withdrawal symptoms, including seizures. A doctor must supervise a gradual tapering of the dose. Misuse and Addiction: The medication has a potential for misuse and addiction, especially in individuals with a history of substance abuse. Interactions with Opioids and Alcohol: Combining alprazolam with opioids, alcohol, or other CNS depressants can lead to severe sedation, life-threatening respiratory depression, coma, and death.