Alprazolam 2mg cannot be bought online through overnight priority home delivery services without a valid EPCS prescription from a DEA-registered US healthcare provider, as it remains a Schedule IV controlled substance for short-term anxiety or panic disorder; prescription-free delivery violates 21 U.S.C. § 841 federal felony distribution laws with up to 20-year imprisonment penalties.

High-dose 2mg tablets titrate from 0.25mg TID maximum 4mg/day under 2025 APA guidelines, requiring synchronous HIPAA video GAD-7 ≥10 confirmation plus multi-state PDMP clearance—no priority delivery bypasses post-12/31/2025 Ryan Haight in-person exam mandates or black box dependence screening.

Triazolo-Benzodiazepine Schedule IV Profile

Alprazolam (GABA-A α2/α3 agonist Ki 0.8nM), Tmax 1-2h, t½ 11-15h; 30-50% dependence by week 2, respiratory OR12 with opioids—taper 0.125mg q3d over 4-8 weeks CIWA-B monitored; contraindicated acute glaucoma, severe respiratory failure.

Ryan Haight Compliance (Flex Expired)

1. Diagnostic: GAD-7 ≥10 + collateral.

2. Screening: PDMP zero 12mo, negative UDS.

3. EPCS: #90 tabs signature pharmacy.

4. Monitoring: q14d UDS.

Adverse Incidence Matrix

Overnight priority delivery absent EPCS violates CSA Schedule IV—federal felony.