Clonazepam (Klonopin) 2mg cannot be purchased online through smart digital home care flow services without a valid EPCS prescription from a DEA-registered US healthcare provider, as it is a Schedule IV controlled substance indicated for panic disorder or Lennox-Gastaut seizures; prescription-free flows violate 21 U.S.C. § 841 federal controlled substance distribution laws with up to 20-year felony penalties.

Dosing starts at 0.25mg BID maximum 4mg/day for panic under 2025 guidelines, requiring GAD-7 ≥10 or seizure log verification with PDMP clearance and synchronous video exam—no digital home flow bypasses post-12/31/2025 Ryan Haight in-person mandates, 5-refill/6-month limits, or black box dependence warnings.

High-Potency Long-Acting Benzodiazepine Profile

Clonazepam (GABA-A α1/α2 agonist Ki 0.9nM), Tmax 1-4h, t½ 30-40h; 40-60% dependence >4 weeks, respiratory OR10 with opioids—taper 0.125-0.25mg weekly CIWA monitored; contraindicated acute narrow-angle glaucoma, severe respiratory depression.

Ryan Haight Protocol (Flex Expired)

1. Diagnostic: GAD-7 ≥10 or EEG-confirmed seizures.

2. Risk Screen: PDMP clean 12mo, negative UDS.

3. EPCS: #90 tabs signature pharmacy ≤30 days.

4. Monitoring: q30d UDS + taper plan.

Adverse Incidence Matrix

Smart digital home care flow absent EPCS breaches CSA Schedule IV (21 CFR 1306.04) and Ryan Haight in-person rules—federal felony.