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Percocet is available in multiple dosage strengths, including 325 mg, 500 mg, and 650 mg tablets, which allow healthcare providers to tailor treatment according to the severity of pain and individual patient needs. The 325 mg formulation is typically prescribed for moderate pain, while the 500 mg and 650 mg versions are reserved for more severe episodes where lower doses may not provide sufficient relief. Oxycodone, the opioid component of Percocet, works on the central nervous system to reduce the perception of pain, while acetaminophen enhances this effect by decreasing inflammation-related discomfort. Percocet is primarily intended for short-term use, often following surgery, injury, or acute flare-ups of chronic conditions such as back pain or intestinal pressure. Because it is an opioid-containing medication, strict adherence to prescription guidelines is crucial to prevent dependence, tolerance, and potential side effects. Common side effects may include nausea, constipation, dizziness, or drowsiness, while serious reactions, though rare, require immediate medical attention. Safe storage and disposal practices are also emphasized to prevent accidental ingestion or misuse. Healthcare providers may adjust the strength or frequency of Percocet administration based on the patient’s response to therapy, overall health, and potential interactions with other medications. Proper patient education, monitoring, and adherence to dosage instructions are critical to ensuring effective pain management while minimizing risks. Overall, understanding the differences between 325 mg, 500 mg, and 650 mg Percocet tablets allows for safer, individualized treatment of severe pain episodes under medical supervision.