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Hydrocodone is a prescription opioid analgesic commonly used to treat moderate to moderately severe pain when non-opioid pain relievers are not effective. It is frequently prescribed after surgery, injury, or for short-term management of acute pain. Hydrocodone works by binding to opioid receptors in the brain and spinal cord, changing how the body perceives and responds to pain.

Hydrocodone is often combined with other medications such as acetaminophen or ibuprofen to enhance pain relief. These combination products can be effective but require careful dosing to avoid complications, particularly liver damage associated with excessive acetaminophen intake. Hydrocodone is available in immediate-release and extended-release formulations, depending on the clinical need.

Common side effects include drowsiness, dizziness, nausea, vomiting, constipation, and slowed reaction time. More serious risks include respiratory depression, low blood pressure, and slowed heart rate, especially when hydrocodone is taken in higher doses or combined with alcohol, benzodiazepines, or other central nervous system depressants. Patients should avoid driving or operating heavy machinery until they understand how the medication affects them.

Long-term or improper use of hydrocodone may lead to tolerance, physical dependence, and misuse. Abruptly stopping the medication can cause withdrawal symptoms such as restlessness, muscle aches, sweating, anxiety, and gastrointestinal discomfort. For this reason, healthcare providers usually recommend using the lowest effective dose for the shortest duration and gradually tapering when discontinuing therapy.