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Tramadol must always be used under medical supervision, regardless of how quickly a patient wishes to access treatment. Doctors typically start with a low dose and adjust slowly based on the patient’s pain level and response. Because Tramadol acts on both opioid and neurotransmitter pathways, precise dosing is important to avoid unwanted effects.

The usual prescribed dosage depends on age, medical history, and whether the patient takes extended-release or immediate-release formulations. Patients should take Tramadol exactly as instructed and never increase their dose on their own. Sudden overuse or mixing Tramadol with alcohol, benzodiazepines, or sedatives can cause dangerous respiratory depression. Individuals taking antidepressants or medications that influence serotonin must be cautious, as combining these with Tramadol may increase the risk of serotonin syndrome.