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Clonazepam (brand name Klonopin®, among others) is a prescription medication belonging to the benzodiazepine class of drugs. It is primarily used to treat seizure disorders and panic disorder. Key Information How it Works: Clonazepam works by enhancing the effects of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. This action helps to calm the nervous system, reduce abnormal electrical activity, and produce anticonvulsant and anti-anxiety effects. Indications: It is FDA-approved for specific conditions and also used off-label for others. Approved uses: Various seizure disorders in adults and children (e.g., Lennox-Gastaut syndrome, myoclonic, and absence seizures). Panic disorder, with or without agoraphobia, in adults. Off-label uses: Restless leg syndrome. Acute mania. Insomnia. Dosage Forms: Clonazepam is available as an oral tablet and an orally disintegrating tablet. Side Effects: Common side effects include drowsiness, dizziness, fatigue, and impaired coordination.