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Tramadol is a prescription medication used to treat moderate to moderately severe pain. It is classified as a centrally acting analgesic with both opioid-like activity and serotonin–norepinephrine reuptake inhibition (SNRI) properties. Because of this dual mechanism, it can help manage different types of pain. ______________ What Tramadol Is Used For 1. Moderate to Severe Pain Doctors prescribe Tramadol for pain caused by: • Injuries • Surgeries • Chronic musculoskeletal conditions • Certain nerve-related pain 2. Chronic Pain Conditions (Extended-Release Form) Extended-release (ER) Tramadol may be used in long-term management of ongoing pain when around-the-clock treatment is needed and other medications are not sufficient. ______________ How Tramadol Works Tramadol relieves pain through two actions: 1. Mu-opioid receptor activation – helps reduce pain signals 2. Serotonin and norepinephrine reuptake inhibition – improves pain modulation within the nervous system This combination makes Tramadol effective for both traditional pain and some neuropathic components. ______________ Forms & Strengths Tramadol is available as: • Immediate-release tablets • Extended-release tablets/capsules • Oral drops or solution (in some regions) A healthcare provider determines the appropriate strength and dosage. ______________ Common Side Effects Some people may experience: • Nausea • Dizziness • Drowsiness • Headache • Constipation • Sweating If symptoms are severe or unusual, medical attention is needed. ______________ Warnings & Precautions Tramadol is a controlled substance in many countries due to risks of: • Dependence • Misuse • Withdrawal • Serious interactions Important safety considerations: • Avoid alcohol and other sedatives • Do not combine with antidepressants or MAOIs without medical advice (risk of serotonin syndrome) • Do not exceed prescribed doses • Individuals with severe breathing problems or seizures should use caution Abruptly stopping long-term use can lead to withdrawal; tapering must be supervised by a doctor. ______________ Important Note Tramadol should only be used with a valid prescription and under medical supervision. Misuse or unsupervised use can lead to addiction, overdose risks, and legal issues.
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