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Subutex is a prescription medication used in the treatment of opioid use disorder (OUD). It contains buprenorphine as its sole active ingredient, which is a partial opioid agonist. Subutex works by reducing withdrawal symptoms and cravings without producing the same intense euphoria as full opioids. It is often used during the initial phase of treatment (induction) and may be preferred in certain situations, such as pregnancy or when naloxone is not tolerated.

Dosages of Subutex are individualized based on the severity of opioid dependence, withdrawal symptoms, and treatment stage. Initial doses usually begin at 2 to 4 mg, administered sublingually (under the tongue), with careful increases as needed. Maintenance doses commonly range from 8 to 24 mg per day. Tablets should be allowed to dissolve completely and should not be chewed, swallowed, or crushed, as improper use can reduce effectiveness or increase side effects.

Important warnings are associated with Subutex use. It should be used cautiously in individuals with respiratory disorders, liver disease, head injury, or a history of substance misuse. Pregnant women may be prescribed Subutex under close supervision, as it may be safer than other opioid treatments but still carries risks. Combining Subutex with alcohol, benzodiazepines, or other central nervous system depressants can cause serious respiratory depression, coma, or death. Abrupt discontinuation may lead to withdrawal symptoms.

Common side effects of Subutex include headache, nausea, constipation, sweating, dizziness, insomnia, and fatigue. More serious side effects may involve slow or shallow breathing, liver problems, allergic reactions, or severe sedation. Long-term use can result in physical dependence, but when taken as prescribed, Subutex significantly lowers the risks associated with illicit opioid use and relapse. Immediate medical attention is required if symptoms such as difficulty breathing, confusion, or yellowing of the skin or eyes occur.

In summary, Subutex is an effective medication for managing opioid dependence when used properly and under medical supervision. Understanding correct dosages, recognizing important warnings, and monitoring for side effects are essential components of safe and successful treatment within a comprehensive recovery program.