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Oxycodone is a prescription opioid analgesic used to manage moderate to severe pain when other pain treatments are insufficient. It works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain and improving comfort. Oxycodone is taken orally, with or without food, and is available in immediate-release and extended-release forms. Tablets should be swallowed whole as directed; extended-release products must not be crushed or chewed.

Dosage is individualized based on pain severity, prior opioid exposure, and patient response. For opioid-naïve adults, immediate-release therapy often begins at 5–10 mg every 4–6 hours as needed, with careful titration. Extended-release formulations are typically taken on a fixed schedule for continuous pain control. Oxycodone can cause drowsiness, constipation, nausea, and slowed breathing, and carries risks of dependence and overdose. Avoid alcohol and other sedatives unless approved. Do not stop abruptly without medical advice. Always use under close supervision of a licensed healthcare professional.