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Percocet is a prescription combination medication used to treat moderate to severe pain. It contains oxycodone, a potent opioid analgesic, and acetaminophen, a non-opioid pain reliever that enhances pain control. By acting on both the central nervous system and pain pathways, Percocet provides effective short-term pain relief, particularly after surgery, injury, or acute medical procedures.

Dosages of Percocet vary depending on the strength of the tablet and the patient’s pain level. Common formulations include 2.5 mg, 5 mg, 7.5 mg, or 10 mg of oxycodone, combined with 325 mg of acetaminophen. Typical adult dosing is one tablet every 6 hours as needed for pain, with strict limits on daily acetaminophen intake. Patients should not exceed 4,000 mg of acetaminophen per day, as higher amounts can cause serious liver damage.

There are important warnings associated with Percocet use. It should not be taken by individuals with severe respiratory depression, asthma, liver disease, or a history of substance abuse without close medical supervision. Pregnant women using Percocet may expose the newborn to neonatal opioid withdrawal syndrome. Combining Percocet with alcohol, benzodiazepines, or other sedatives greatly increases the risk of life-threatening respiratory depression, coma, or overdose.

Common side effects include drowsiness, dizziness, nausea, vomiting, constipation, itching, and dry mouth. More serious side effects may involve slow or shallow breathing, confusion, low blood pressure, allergic reactions, or severe sedation. Long-term or improper use can lead to tolerance, physical dependence, addiction, and liver injury due to acetaminophen. Immediate medical attention is required if symptoms such as difficulty breathing, extreme sleepiness, or yellowing of the skin or eyes occur.

Percocet can be an effective medication for acute pain management when used exactly as prescribed and under medical supervision. Understanding appropriate dosages, recognizing key warnings, and being aware of potential side effects are essential for ensuring safe and responsible use of this opioid combination medication.