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Percocet is a prescription pain medication that combines oxycodone (an opioid analgesic) with acetaminophen (a non-opioid pain reliever). It is used to treat moderate to severe pain, often after surgery, injury, or during acute pain episodes when other medications are not sufficient. Oxycodone works on the central nervous system to reduce pain perception, while acetaminophen enhances overall pain relief.

Dosage of Percocet depends on the strength prescribed and the patient’s pain severity, tolerance, and medical history. Typical adult dosing ranges from 1 tablet every 4–6 hours as needed for pain, with tablet strengths commonly containing 2.5 mg, 5 mg, 7.5 mg, or 10 mg of oxycodone combined with 325 mg of acetaminophen. Patients must be careful not to exceed the maximum daily acetaminophen limit (generally 3,000–4,000 mg per day) to avoid serious liver damage. Percocet should be taken exactly as prescribed and never in higher or more frequent doses.

There are important warnings associated with Percocet use. Because it contains an opioid, it carries a high risk of misuse, addiction, and physical dependence, even when used as directed. Percocet can cause respiratory depression, meaning slow or shallow breathing, especially at higher doses or when combined with alcohol, benzodiazepines, or other sedatives. Long-term use or abrupt discontinuation may result in withdrawal symptoms such as restlessness, muscle pain, nausea, and sweating.

Common side effects of Percocet include drowsiness, constipation, nausea, vomiting, dizziness, and itching. More serious side effects may include confusion, low blood pressure, slow breathing, or signs of liver injury such as yellowing of the skin or eyes. Patients should avoid driving or operating heavy machinery until they know how the medication affects them and should seek immediate medical attention if symptoms of overdose occur, including extreme sleepiness, difficulty breathing, or loss of consciousness.